Epithelial ovarian cancer in patients under 20 years of age / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
;
: 850-857, 2008.
Article
in Korean
| WPRIM
| ID: wpr-194094
ABSTRACT
OBJECTIVE:
Epithelial ovarian cancer is the most common cause of death due to gynecologic malignancies in adults, but is rare in children and adolescents. This is a report of series of such patients under 20 years of age documenting their presentation, histologic type, stage of disease, treatment, and outcome.METHODS:
We collected data on 21 patients with epithelial ovarian cancer under 20 years of age between January 1990 and December 2005. Patient records and pathology were reviewed.RESULTS:
Epithelial ovarian cancer under 20 years of age was 2.2% in overall ovarian cancer. Epithelial ovarian cancer was 42.0% among 50 patients under 20 years of age and the most common histologic type was germ cell tumors (54%). The median age at the time of diagnosis was 17.6 years (range, 13-20 years), and the median follow-up was 87 months (range, 4-175 months). There were seventeen (81.0%) mucinous tumors, four (19.0%) serous tumors. About thirty-eight percent were low malignant potential or borderline tumors. About Eighty-five percent (18 patients) of tumors were stage I disease and about fourteen percent (3 patients) were stage III disease at the time of diagnosis. Surgical treatment included conservative surgery in 18 patients (85.7%), total abdominal hysterectomy and bilateral salpingo- oophorectomy in 3 patients (14.3%).CONCLUSION:
Epithelial ovarian cancers are rare in patients in children and adolescents. The majority of ovarian cancers in this age group are mucinous tumors, stage I at diagnosis and borderline ovarian tumor. Conservative management is feasible to achieve preservation of fertility.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovarian Neoplasms
/
Ovariectomy
/
Follow-Up Studies
/
Cause of Death
/
Neoplasms, Glandular and Epithelial
/
Neoplasms, Germ Cell and Embryonal
/
Fertility
/
Hysterectomy
/
Mucins
Type of study:
Observational study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
2008
Type:
Article
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