Clinical Characteristics of 75 Patients with Leukemia Cutis
Journal of Korean Medical Science
;
: 614-619, 2013.
Article
in English
| WPRIM
| ID: wpr-194139
ABSTRACT
Leukemia cutis (LC) is defined as a neoplastic leukocytic infiltration of the skin. Few clinical studies are available on recent trends of LC in Korea. The purpose of this study was to analyze the clinical features and prognosis of LC in Korea and to compare findings with previous studies. We performed a retrospective study of 75 patients with LC and evaluated the patients' age and sex, clinical features and skin lesion distribution according to the type of leukemia, interval between the diagnosis of leukemia and the development of LC, and prognosis. The male to female ratio was 21, and the mean age at diagnosis was 37.6 yr. The most common cutaneous lesions were nodules. The most commonly affected site was the extremities in acute myelocytic leukemia and chronic myelocytic leukemia except for acute lymphocytic leukemia. Compared with previous studies, there was an increasing tendency in the proportion of males and nodular lesions, and LC most often occurred in the extremities. The prognosis of LC was still poor within 1 yr, which was similar to the results of previous studies. These results suggest that there is a difference in the clinical characteristics and predilection sites according to type of leukemia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
/
Leukemia, Myeloid, Acute
/
Retrospective Studies
/
Leukemic Infiltration
/
Extremities
/
Neoplasm Staging
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Journal of Korean Medical Science
Year:
2013
Type:
Article
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