Use of Splenectomy to Treat Evans Syndrome Following an ABO-Matched Liver Transplant / 대한내과학회지
Korean Journal of Medicine
;
: 464-468, 2015.
Article
in English
| WPRIM
| ID: wpr-194216
ABSTRACT
Evans syndrome is a rare complication that develops in adults after liver transplantation. The possible etiologies include ABO mismatch, viral infection, post-transplantation lymphoproliferative disease, graft-versus-host disease, and the use of certain immunosuppressive drugs (e.g., calcineurin inhibitors). Here, we present a case of Evans syndrome that developed after an ABO-matched liver transplant. Glucocorticosteroid, intravenous immunoglobulin, and alternative immunosuppressant therapies all failed. Weekly rituximab (375 mg/m2) was then administered for 4 weeks. The cytopenia improved transiently after the second dose of rituximab, but soon worsened again. However, the cytopenia normalized after a splenectomy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Splenectomy
/
Immunoglobulins
/
Liver Transplantation
/
Purpura, Thrombocytopenic, Idiopathic
/
Calcineurin
/
Rituximab
/
Graft vs Host Disease
/
Anemia, Hemolytic, Autoimmune
/
Liver
Limits:
Adult
/
Humans
Language:
English
Journal:
Korean Journal of Medicine
Year:
2015
Type:
Article
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