Occupational asthma induced by beat-galactosidase
Allergy, Asthma & Respiratory Disease
;
: 75-77, 2014.
Article
in Korean
| WPRIM
| ID: wpr-19436
ABSTRACT
Galactosidase is generated from Aspergillus oryzae, which is widely used for antidiarrhea medicine to infants. Antibiotics and digestives were reported as a causative allergen inducing occupational asthma. Galatosidase-induced occupational asthma has not been reported yet. A forty-year-old female has suffered from rhinorrhea, sneezing, and nasal obstruction 1 year after handling galactosidase at obstetric and pediatric hospital, and then dyspnea appeared later. Skin prick test with inhalent allergens, beta-galactosidase, and Aspergillus oryzae showed strong positive reaction to beta-galactosidase only. Immunoinhibition test with beta-galactosidase and A. oryzae revealed inhibition to beta-galactosidase only. Bronchial provocation test with beta-galactosidase showed the dual asthmatic response. With these results, we confirmed that the patient has beta-galactosidase-induced occupational asthma and rhinitis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Aspergillus oryzae
/
Oryza
/
Skin
/
Sneezing
/
Bronchial Provocation Tests
/
Allergens
/
Nasal Obstruction
/
Rhinitis
/
Beta-Galactosidase
/
Dyspnea
Limits:
Female
/
Humans
/
Infant
Language:
Korean
Journal:
Allergy, Asthma & Respiratory Disease
Year:
2014
Type:
Article
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