Evaluation of Platelet Concentrates Stored in the Second Generation Platelet Storage Containers / 대한수혈학회지
Korean Journal of Blood Transfusion
; : 49-57, 1997.
Article
in Ko
| WPRIM
| ID: wpr-195275
Responsible library:
WPRO
ABSTRACT
BACKGROUND: Platelets can be stored for 3days at 22degrees C in conventional plastic bags plasticizer with di-(2-ethylhexyl)phthalate(DEHP). However, with such a short interval for storage, platelets could not be made easily available for thrombocytopenic patients. In vitro platelet function during 5 days of storage at 22degrees C was studied in a new plastic bag (second generation bag) which contained as plasticizer a tri (2-ethylhexyl)trimellitate and developed in Korea (Boin Medica Co.). METHODS: In vitro function (mean platelet volume, platelet distribution width, pH, platelet aggregation, platelet morphology and swirling phenomenon) was evaluated in 20 units of platelet concentrate at day 0, 2, 5 while mixing in 60 rpm platelet rotator at 22degrees C. RESULTS: At day 5, platelet count, mean platelet volume, platelet distribution width, pH, platelet aggregation, platelet morphology and swirling phenomenon were well maintained. pO2, pCO2 and HCO3- were 65.6mmHg, 43.4mmHg and 12.3mmol/L at day 5, respectively. CONCLUSION: The data indicate that the use of the new platelet storage container will permit satisfactory storage for at least 5 days at 22degrees C.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Plastics
/
Platelet Count
/
Blood Platelets
/
Platelet Aggregation
/
Mean Platelet Volume
/
Hydrogen-Ion Concentration
/
Korea
Limits:
Humans
Country/Region as subject:
Asia
Language:
Ko
Journal:
Korean Journal of Blood Transfusion
Year:
1997
Type:
Article