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Prevalence of Irritable Bowel Syndrome–like Symptoms in Japanese Patients with Inactive Inflammatory Bowel Disease
Journal of Neurogastroenterology and Motility ; : 661-669, 2016.
Article in English | WPRIM | ID: wpr-195313
ABSTRACT
BACKGROUND/

AIMS:

Few studies are available that have investigated the risk factors for overlapping irritable bowel syndrome (IBS)-like symptoms in patients with inactive inflammatory bowel disease (IBD). The present study has 3

objectives:

(1) to assess the prevalence of IBS-like symptoms in Japanese patients with inactive IBD using Rome III criteria, (2) to examine the relationship of IBS-like symptoms to health related quality of life (HR-QOL), and (3) to investigate associations for developing IBS-like symptoms in patients with inactive IBD.

METHODS:

IBS-like symptoms were evaluated using the Rome III questionnaire for functional gastrointestinal disorders. HR-QOL and hospital anxiety and depression scale were evaluated.

RESULTS:

IBS-like symptoms were found in 17.5% (7/40) of patients with inactive ulcerative colitis, 27.1% (29/107) of patients with inactive Crohn’s disease (CD), and 5.3% (23/438) of healthy control subjects. The QOL level was significantly lower and anxiety score was significantly higher in inactive CD patients with IBS-like symptoms than in those without such symptoms (P = 0.003, P = 0.009). Use of anti-anxiety drugs was associated with the presence of IBS symptoms (P = 0.045). HR-QOL score was lower and anxiety score was higher in patients with inactive ulcerative colitis, but the difference was not statistically significant.

CONCLUSIONS:

The prevalence of IBS-like symptoms in inactive IBD patients was significantly higher than in healthy controls. Inactive CD patients with IBS-like symptoms has low QOL and anxiety; suggesting that anxiety may be associated with symptom development in such patients.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Anxiety / Quality of Life / Anti-Anxiety Agents / Inflammatory Bowel Diseases / Colitis, Ulcerative / Prevalence / Risk Factors / Irritable Bowel Syndrome / Asian People / Depression Type of study: Diagnostic study / Etiology study / Prevalence study / Risk factors Limits: Humans Language: English Journal: Journal of Neurogastroenterology and Motility Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Anxiety / Quality of Life / Anti-Anxiety Agents / Inflammatory Bowel Diseases / Colitis, Ulcerative / Prevalence / Risk Factors / Irritable Bowel Syndrome / Asian People / Depression Type of study: Diagnostic study / Etiology study / Prevalence study / Risk factors Limits: Humans Language: English Journal: Journal of Neurogastroenterology and Motility Year: 2016 Type: Article