Prevalence of Irritable Bowel Syndrome–like Symptoms in Japanese Patients with Inactive Inflammatory Bowel Disease
Journal of Neurogastroenterology and Motility
;
: 661-669, 2016.
Article
in English
| WPRIM
| ID: wpr-195313
ABSTRACT
BACKGROUND/AIMS:
Few studies are available that have investigated the risk factors for overlapping irritable bowel syndrome (IBS)-like symptoms in patients with inactive inflammatory bowel disease (IBD). The present study has 3objectives:
(1) to assess the prevalence of IBS-like symptoms in Japanese patients with inactive IBD using Rome III criteria, (2) to examine the relationship of IBS-like symptoms to health related quality of life (HR-QOL), and (3) to investigate associations for developing IBS-like symptoms in patients with inactive IBD.METHODS:
IBS-like symptoms were evaluated using the Rome III questionnaire for functional gastrointestinal disorders. HR-QOL and hospital anxiety and depression scale were evaluated.RESULTS:
IBS-like symptoms were found in 17.5% (7/40) of patients with inactive ulcerative colitis, 27.1% (29/107) of patients with inactive Crohn’s disease (CD), and 5.3% (23/438) of healthy control subjects. The QOL level was significantly lower and anxiety score was significantly higher in inactive CD patients with IBS-like symptoms than in those without such symptoms (P = 0.003, P = 0.009). Use of anti-anxiety drugs was associated with the presence of IBS symptoms (P = 0.045). HR-QOL score was lower and anxiety score was higher in patients with inactive ulcerative colitis, but the difference was not statistically significant.CONCLUSIONS:
The prevalence of IBS-like symptoms in inactive IBD patients was significantly higher than in healthy controls. Inactive CD patients with IBS-like symptoms has low QOL and anxiety; suggesting that anxiety may be associated with symptom development in such patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Anxiety
/
Quality of Life
/
Anti-Anxiety Agents
/
Inflammatory Bowel Diseases
/
Colitis, Ulcerative
/
Prevalence
/
Risk Factors
/
Irritable Bowel Syndrome
/
Asian People
/
Depression
Type of study:
Diagnostic study
/
Etiology study
/
Prevalence study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Journal of Neurogastroenterology and Motility
Year:
2016
Type:
Article
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