Inhibitory Effects of Cough Reflex Induced from Fentanyl According to the Dose of Propofol / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 595-598, 1999.
Article
in Korean
| WPRIM
| ID: wpr-195429
ABSTRACT
BACKGROUND:
Bronchodilation effect of propofol was known that it could prevent bronchoconstriction induced by fentanyl administration. The aim of this study was to investigate the dosage of propofol that inhibited cough reflex induced from fentanyl.METHODS:
One hundred twenty patients were randomly allocated to four groups Group 1 (n=30, fentanyl 3 microgram/kg), Group 2 (n=30, propofol 0.5 mg/kg, fentanyl 3 microgram/kg), Group 3 (n=30, propofol 1 mg/kg, fentanyl 3 microgram/kg), Group 4 (n=30, propofol 2 mg/kg, fentanyl 3 microgram/kg). Patients in Group 1 were injected fentanyl within a second. Other patients groups were injected fentanyl two minutes after administration of propofol dosage, respectively. We checked cough response, oxygen desaturation and chest wall rigidity.RESULTS:
There was no significant difference in the incidence of cough response between Group 1 and 2. But, the incidence of Group 3 and 4 was significantly lower than in Group 1 and 2.CONCLUSIONS:
Propofol of clinical doses for anesthetic induction inhibit cough reflex induced from fentanyl.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oxygen
/
Reflex
/
Propofol
/
Fentanyl
/
Incidence
/
Bronchoconstriction
/
Cough
/
Thoracic Wall
Type of study:
Incidence study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
1999
Type:
Article
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