Factors associated low HDL cholesterol in adults

ABSTRACT

BACKGROUND: Coronary artery disease are increasing in recent years among Korean due to change of dietary pattern. We conducted a cross sectional study to analyze various factors for low HDL cholesterol knowns as a independent risk factor for coronary artery disease. METHODS: At the health care center of Asan Medical Center in 1999, 7259 people without cardiovascular disease, cerebrovascular disease, hyperlipidemia were selected. They were exmined weight, height, blood pressure. Other data was drawn from questionnaire, blood chemistry. SPSS (version 7.5) was used for analysis of this data. RESULTS: 1) The means of HDL cholesterol level was higher in women than men. 2) The means of HDL cholesterol of men was lower in subgroup of age below 45 years old, obesity, lower total cholesterol( OR =200 mg/dL), current smoking, sedantary life style than others. In women, it was lower in subgroup of over 55 years old, obesity, diabetes, hypertention, lower total cholesterol( OR =200 mg/dL) than others. By multilple logistic analysis, obesity, triglyceride, current smoking, moderate alcohol drinking were significant factors associated with low HDL cholesterol (< 42 mg/dL, 25 percentile of study paricipants). CONCLUSION: These resluts suggest that obesity, high triglyceride, current smoking are independent risk factors and moderate alcoholic drinking is a negative risk factor of low HDL cholesterol in this study participants.