Are Serum Vitamin D Levels Associated With Dry Eye Disease? Results From the Study Group for Environmental Eye Disease / 예방의학회지
Journal of Preventive Medicine and Public Health
;
: 369-376, 2017.
Article
in English
| WPRIM
| ID: wpr-196774
ABSTRACT
OBJECTIVES:
Dry eye disease (DED) is an increasingly important public health problem in Korea. Previous studies conducted in Korea have reported inconsistent results regarding the protective effects of vitamin D on DED, and these discrepancies may be related to the relatively simple questionnaire that has been used. Thus, we evaluated the association of serum vitamin D levels with DED using the ocular surface disease index (OSDI).METHODS:
The present study evaluated data from participants in the Study Group for Environmental Eye Disease (2014-2015). This group included data from 752 participants, and data from 740 participants (253 men and 487 women) were analyzed in the present study. DED severity was evaluated using the OSDI.RESULTS:
Higher serum vitamin D levels were associated with a non-significantly reduced risk of DED in the crude analysis (odds ratio [OR], 0.991; 95% confidence interval [CI], 0.971 to 1.011) and in the adjusted analysis (OR, 0.988; 95% CI, 0.966 to 1.010). In the crude analysis of no/mild DED vs. moderate/severe DED, men exhibited a decreased risk with increasing serum vitamin D levels (OR, 0.999; 95% CI, 0.950 to 1.051), while women exhibited an increased risk (OR, 1.003; 95% CI, 0.979 to 1.027). In these analyses, we found no significant associations.CONCLUSIONS:
The findings of the present study support previous reports that serum vitamin D levels are not associated with DED.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Vitamin D
/
Vitamins
/
Dry Eye Syndromes
/
25-Hydroxyvitamin D 2
/
Keratoconjunctivitis Sicca
/
Public Health
/
Eye Diseases
/
Korea
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Journal of Preventive Medicine and Public Health
Year:
2017
Type:
Article
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