The Clinical Effects of Cefpirome for the Treatment of Acute Lower Respiratory Infection / 영남의대학술지
Yeungnam University Journal of Medicine
;
: 219-227, 1999.
Article
in Korean
| WPRIM
| ID: wpr-197111
ABSTRACT
BACKGROUND:
In contrast to a healthy person, patients who have acute lower pespiratory tract infection with underlying pulmonary diseases have various pathogens, a rapidly progressie downhill course, and a poor response to prior antimicrobial therapy. Broad spectrum antivacterial therapy is needed for full evaluation. MATERIALS ANDMETHODS:
To evaluate the efficacy and safety of cefpirome, we administered 1gm cefpirome, twice a day to 30 patients who had signs and symptoms of acute lower repiratory infection regardless of their underlying disease, except to those who had an allergic history to antibiotics or severe systemic diseases.RESULTS:
The results were as follows 1) Among 30 cases, 21 cases(70.0%) showed excellent improvement, and 7 cases(23.3%) showed good improvement in their symptoms and signs of acute lower respiratory infection. 2) In 14 cases with isolated pathogens, we observed bacteriologic eradication in 11 cases(78.6%). 3) Significant side effects were not foundCONCLUSION:
Above results suggest that cefpirome was effective as a monotherapy in patients with acute lower respriatory infection, especially on those with as underlying chronic obstructive pulmonary disease(COPD).
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pulmonary Disease, Chronic Obstructive
/
Lung Diseases
/
Anti-Bacterial Agents
Limits:
Humans
Language:
Korean
Journal:
Yeungnam University Journal of Medicine
Year:
1999
Type:
Article
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