Correlation between periodontitis and chronic kidney disease in Korean adults
Kidney Research and Clinical Practice
;
: 164-170, 2013.
Article
in English
| WPRIM
| ID: wpr-197124
ABSTRACT
BACKGROUND:
Periodontitis and chronic kidney disease (CKD) are important health issues; however,the association between periodontitis and CKD markers, especially in Korean adults,remains elusive.METHODS:
Data on 15,729 Korean adults were obtained from the Korean National Health and Nutritional Examination Surveys IV and V. The CKD markers included a decreased estimated glomerular filtration rate (eGFR;<60 mL/min/1.73m2), proteinuria, and hematuria. Odds ratios (ORs) and 95% confidence intervals were measured using stepwise multivariate logistic regression analyses for CKD markers based on the presence of periodontitis.RESULTS:
Patients with periodontitis had greater unadjusted ORs for CKD markers compared to those without periodontitis, as follows decreased eGFR,4.07(3.11-5.33); proteinuria, 2.12(1.48-3.05); and hematuria, 1.25 (1.13-1.39, all P<0.001). Periodontitis was a significant predictor of decreased eGFR independent of allcovariates [1.39 (1.03-1.89), P=0.034]. However, the effect of periodontitis on decreased eGFR seemed to be affected by hypertension and diabetes mellitus. Periodontitis was not an independent predictor of proteinuria; the significance disappeared after adjusting for hypertension and diabetes mellitus. Periodontitis was significantly correlated with hematuria, leading to similar ORs regardless of the adjustment for covariates[1.29 (1.15-1.46), P<0.001].CONCLUSION:
This study confirms the correlation between periodontitis and CKD markers, including decreased eGFR, proteinuria, and hematuria in Korean adults.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Periodontal Diseases
/
Periodontitis
/
Proteinuria
/
Logistic Models
/
Odds Ratio
/
Diabetes Mellitus
/
Renal Insufficiency, Chronic
/
Glomerular Filtration Rate
/
Hematuria
/
Hypertension
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Humans
Language:
English
Journal:
Kidney Research and Clinical Practice
Year:
2013
Type:
Article
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