Propranolol Hcl in Patients with Angina Pectoris
Korean Circulation Journal
;
: 43-48, 1971.
Article
in Korean
| WPRIM
| ID: wpr-197130
ABSTRACT
A double-blind trial of the efficacy of propranolol hydrochloride a new beta adrenergic blocking agent, in the prophylactic treatment of angina pectoris was conducted in 9 patients. Through the trial period of 8 weeks to more than 26 weeks, the patients received propranolol and placebo for equal period. Following are the results. 1. The effective dose of propranolol hydrochloride in the prophylactic treatment of angina pectoris was 80 mg to 120 mg per day. 2. The effectiveness of propranolol hydrochloride was manifested by a reduction in frequency of pain to 40.7%, in nitroglycerin comsumption to 38.8% and by an increase in exercise tolerance. 3. Obseved side effects were transient nausea, vomiting and bradycardia, which were improved with reduction in drug dosage. 4. Further clinical and experimental information may be necessary in order to assess the long-term effects of propranolol hydrochloride.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Propranolol
/
Vomiting
/
Bradycardia
/
Nitroglycerin
/
Exercise Tolerance
/
Angina Pectoris
/
Nausea
Type of study:
Controlled clinical trial
Limits:
Humans
Language:
Korean
Journal:
Korean Circulation Journal
Year:
1971
Type:
Article
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