A Case of Thrombotic Thrombocytopenic Purpura Associated with Ticlopidine
Journal of the Korean Neurological Association
;
: 512-514, 2000.
Article
in Korean
| WPRIM
| ID: wpr-197458
ABSTRACT
Ticlopidine, a widely used antiplatelet agent, has been rarely reported to cause thrombotic thrombocytopenic purpura (TTP). To the best of our knowledge, its occurrence has never before been reported in Korea. A 69 years old female patient suffered from an acute ischemic stroke. Ticlopidine 250mg bid was started and she followed an uneventful clin-ical course. The platelet count was normal on the 1st and the 12th day of ticlopidine administration. Around the 31st day, at home, she developed purpura, dyspnea and a stuporous mental status. Under the diagnosis of TTP, a plasma exchange was performed and her condition eventually returned to the baseline status. Ticlopidine induced TTP can developed abruptly despite close monitoring of platelet count, as illustrated by this case. Physicians prescribing ticlopi-dine should be aware of this potentially dangerous complication.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plasma Exchange
/
Platelet Count
/
Purpura
/
Purpura, Thrombotic Thrombocytopenic
/
Ticlopidine
/
Stroke
/
Diagnosis
/
Dyspnea
/
Stupor
/
Korea
Type of study:
Diagnostic study
Limits:
Aged
/
Female
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of the Korean Neurological Association
Year:
2000
Type:
Article
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