Fetal Plasma Cortisol and Dehydroepiandrosterone Sulfate in Pregnancy and Term Parturition / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
;
: 1685-1690, 2001.
Article
in Korean
| WPRIM
| ID: wpr-198316
ABSTRACT
OBJECTIVE:
The role of steroid hormones in the control of human parturition has been a subject of debate. The objective of the study was to examine if changes in fetal plasma cortisol or dehydroepiandrosterone sulfate (DHEA-S) are associated with human term parturition.METHODS:
Fetal plasma cortisol and DHEA-S were measured in 374 singleton pregnancies delivered at term. Umbilical cord blood was obtained from patients in the following 6 groups 1) preterm gestations undergoing cordocentesis for clinical indications before 36 weeks of gestation (n=93), 2) women undergoing cordocentesis for clinical indications after 36 weeks of gestation (n=9), 3) elective cesarean section (C/S) at term without labor (n=140), 4) C/S at term with early labor (cervical dilatationp36 weeks) but did not increase during active labor; 4) The cortisol/ DHEA-S ratio (stress index) increased with advancing gestation and with active labor at term.CONCLUSION:
Human parturition at term is associated with an increase in fetal plasma cortisol and cortisol/DHEA-S ratio, but not DHEA-S.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plasma
/
Hydrocortisone
/
Cesarean Section
/
Cordocentesis
/
Adrenal Cortex Hormones
/
Dehydroepiandrosterone
/
Dehydroepiandrosterone Sulfate
/
Parturition
/
Dilatation
/
Fetal Blood
Limits:
Female
/
Humans
/
Pregnancy
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
2001
Type:
Article
Similar
MEDLINE
...
LILACS
LIS