A Clinical Comparison of Pancuronium and Succinylcho! ine for Cesarean Section Anesthesia / 대한마취과학회지

ABSTRACT

In this study, we adopted two different general anesthetic techniques for Cesarean section. Patients were randomly assigned to two groups; Group I ; 51 patients, thiopental-succinylcholine-nitrous oxide-oxygen supplemented with ether or halothans anesthesia. Group II 67 patients, pancuronium-thiopental-nitrous oxide-oxygen supplemented with ether or halothane anesthesia. Group I (Succinylcholine group) 51cases were induced for anesthesia with 150~250mg of thiopental and intubated with 1mg/ kg of succinylcholine followed by 100% oxygen with controlled ventilation. After delivering the fetus, anesthesia was maintained with nitrous oxide-oxygen-ether or halothane throughout- the procedure. Group III (Pancuronium group); Anesthesia was performed with150~250mg of thiopental, 0. 08mg/kg of pancuronium with endotracheal intubation for 67 patients. After delivery, nitrous oxide with oxygen and supplemental ether or halothane were given, if necessary. It was concluded that incidence of hypotension was less in the pancuronium group, and no evidence of fetal effects was seen. And there is no clinical evidence of significant placental transfer of pancuronium and that this is a safe and efficacious agent for incorporation into the nitrous oxide-relaxant anesthetic technique for Cesarean section. No clear superiority of succinylcholine over pancuronium was demonstrated in this study.