Association between Lower Urinary Tract Symptoms and Erectile Dysfunction in Aging Men: Hallym Aging Study / 대한비뇨기과학회지

ABSTRACT

PURPOSE: The aim of this study was to investigate the relationship between lower urinary tract symptoms(LUTS) and erectile dysfunction(ED) in a population-based cohort study, Hallym Aging Study(HAS). MATERIALS AND METHODS: Among the 1,520 participants in HAS, 300 men aged > or=50 years, who underwent detailed health evaluations, includeing health-related questionnaires, evaluation of the medical history and various life style factors as well as clinical measurements, were included in the study. LUTS and ED were assessed by validated questionnaires, the International Prostate Symptom Score(IPSS) and a 5-item version of the International Index of Erectile Function(IIEF-5). RESULTS: The prevalence and severity of LUTS and ED increased and significantly with age(p<0.001). The IIEF-5 score declined as the severity of LUTS increased in each age group. There was a significant negative correlation between the IPSS score and the IIEF-5 score(age adjusted r= ?0.275, p<0.001). The multivariate logistic regression analysis, controlling for age and comorbidities, showed that men with moderate/ severe LUTS were 4-9 times more likely to have ED than men with no/mild LUTS; in addition, men with ED were 5 times more likely have moderate/severe LUTS than men without ED. CONCLUSIONS: The presence and severity of LUTS were independent risk factors for ED and vice versa. These results highlight the clinical importance of evaluating LUTS in patients with ED, and the need to consider the presence of ED in the management of patients with LUTS