Cyclosporine A as a Primary Treatment for Panniculitis-like T Cell Lymphoma: A Case with a Long-Term Remission / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
;
: 312-316, 2014.
Article
in English
| WPRIM
| ID: wpr-199239
ABSTRACT
Subcutaneous panniculitis-like T cell lymphoma (SPTL) is a distinctive cutaneous lymphoma characterized by an infiltration of subcutaneous tissue by neoplastic T cells, similar to panniculitis. It is well-established that patients who are diagnosed with SPTL usually respond poorly to chemotherapy, showing fatal outcome. As a first line treatment for SPTL, anthracycline-based chemotherapy was most frequently used. For the treatment of SPTL, the efficacy of cyclosporine A has been recently reported in relapsed SPTL after anthracycline-based chemotherapy. However, it is still not clear whether cyclosporine A can be used as a first-line treatment against SPTL. Here, we report a case of SPTL, which achieved complete remission for nine years after first-line cyclosporine A therapy. This study suggests that cyclosporine A can induce a complete long-term remission as a first-line treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
T-Lymphocytes
/
Panniculitis
/
Lymphoma, T-Cell
/
Cyclosporine
/
Fatal Outcome
/
Subcutaneous Tissue
/
Drug Therapy
/
Lymphoma
Limits:
Humans
Language:
English
Journal:
Cancer Research and Treatment
Year:
2014
Type:
Article
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