Primary T-cell Lymphoma of the Thyroid Associated with Hashimoto's Thyroiditis, Histologically Mimicking MALT-Lymphoma
Journal of Korean Medical Science
; : 481-484, 2010.
Article
in En
| WPRIM
| ID: wpr-199407
Responsible library:
WPRO
ABSTRACT
Most of thyroid lymphomas are B-lineage, and T-cell lymphomas are rare. Here, we report a case of primary thyroid T-cell lymphoma associated with Hashimoto's thyroiditis. A 48-yr-old woman presented with incidentally found neck mass. Histologically, the resected right lobe of the thyroid was replaced by monomorphic small atypical lymphoid cells with lymphoepithelial lesion-like change, most of which were immunoreactive for CD3, CD8, betaF-1, and TIA-1. Peripheral T-cell lymphoma, unspecified, was finally diagnosed after molecular study for TCR-gamma gene rearrangement. This is the second case of cytotoxic T-cell lymphoma reported in the thyroid gland so far. Unique association between thyroid follicles and neoplastic lymphocytes may be characteristic feature of this type of T-cell lymphoma.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Thyroid Gland
/
T-Lymphocytes, Cytotoxic
/
T-Lymphocyte Subsets
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Lymphoma, T-Cell
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Lymphoma, B-Cell, Marginal Zone
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Hashimoto Disease
Limits:
Female
/
Humans
Language:
En
Journal:
Journal of Korean Medical Science
Year:
2010
Type:
Article