Peripheral eosinophilia - is it a predictable factor associated with eosinophilic cholecystitis?
Korean Journal of Hepato-Biliary-Pancreatic Surgery
;
: 65-69, 2012.
Article
in English
| WPRIM
| ID: wpr-199656
ABSTRACT
BACKGROUNDS/AIMS:
The purpose of this study was to evaluate the role of peripheral eosinophilia as a predictable factor associated with Eosinophilic cholecystitis (EC) compared with other forms of cholecystitis in patients who underwent a cholecystectomy.METHODS:
Between January 2001 and May 2011, the histopathologic features of 3,539 cholecystectomy specimens were reviewed retrospectively. EC was diagnosed in 30 specimens (0.84%). Data from 30 consecutive patients with EC (eosinophilic cholecystitis group [E-group]) were compared with a retrospective control group of 60 patients (other cholecystitis group [O-group]) during the same period. The two groups were matched for age, gender, and the presence of cholelithiasis.RESULTS:
The median absolute eosinophil count 1 day post-operatively was 144 cells/mm3 (range 9-801 cells/mm3) in the E-group and 93 cells/mm3 (range 0-490 cells/mm3) in the O-group (p=0.036). Pre-operative peripheral eosinophilia was more common in the E-group than the O-group (20% vs. 3.3%, p=0.015). Multivariate analysis revealed that pre-operative peripheral eosinophilia was an independent significant predictable factor associated with EC (odds ratio=7.250, 1.365 <95% confidence interval<38.494, p=0.020).CONCLUSIONS:
In the present study, pre-operative peripheral eosinophilia was shown to be an independent predictable factor associated with EC. Further researches seem to be necessary to confirm this finding.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Cholecystectomy
/
Cholecystitis
/
Multivariate Analysis
/
Retrospective Studies
/
Eosinophilia
/
Eosinophils
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Korean Journal of Hepato-Biliary-Pancreatic Surgery
Year:
2012
Type:
Article
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