The Inflammation Markers According to the Presence of Coronary Artery Disease in Patients with Peripheral Artery Disease
Journal of Lipid and Atherosclerosis
;
: 61-67, 2013.
Article
in Korean
| WPRIM
| ID: wpr-199872
ABSTRACT
OBJECTIVE:
Prevalence of coronary artery disease (CAD) has been reported to be high in patients with atherosclerotic peripheral artery disease (PAD) in lower extremities. Various inflammatory markers have been known to be associated with CAD. The aim of study was to explore the role of inflammatory makers for CAD in patients with PAD.METHODS:
A total of 346 PAD patients (71.51+/-9.41 years, 337 males) who underwent percutaneous transluminal angioplasty from June 2006 to April 2012 were included in this study. Patients were divided into the Group I (PAD with CAD n=151, 149 males) and the Group II (PAD without CAD n=195, 188 males).RESULTS:
Among 346 patients, 149 patients had CAD (43.6%). The prevalence of diabetes mellitus (DM) (p=0.023) and smoking (p=0.010) were significantly higher in the group I when compared withthe group II. The level of high sensitivity C-reactive protein (hs-CRP) increased (p or =3.0 mg/dL) (OR=2.595, 95% CI 1.548-4.350, p<0.001), and age (OR=0.645; 95% CI, 0.454-0.915; p=0.014) were independent predictors for the development of CAD in PAD patients.CONCLUSION:
43.6% of patients with PAD also had CAD, and the predictors of CAD were smoking, DM, and high level of hs-CRP.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Smoke
/
Coronary Artery Disease
/
C-Reactive Protein
/
Smoking
/
Logistic Models
/
Prevalence
/
Angioplasty
/
Coronary Vessels
/
Lower Extremity
/
Diabetes Mellitus
Type of study:
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
Korean
Journal:
Journal of Lipid and Atherosclerosis
Year:
2013
Type:
Article
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