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Computed Tomography Guided Percutaneous Injection of a Mixture of Lipiodol and Methylene Blue in Rabbit Lungs: Evaluation of Localization Ability for Video-Assisted Thoracoscopic Surgery
Journal of Korean Medical Science ; : 129-136, 2014.
Article in English | WPRIM | ID: wpr-200215
ABSTRACT
Preoperative localization is necessary prior to video assisted thoracoscopic surgery for the detection of small or deeply located lung nodules. We compared the localization ability of a mixture of lipiodol and methylene blue (MLM) (0.6 mL, 15) to methylene blue (0.5 mL) in rabbit lungs. CT-guided percutaneous injections were performed in 21 subjects with MLM and methylene blue. We measured the extent of staining on freshly excised lung and evaluated the subjective localization ability with 4 point scales at 6 and 24 hr after injections. For MLM, radio-opacity was evaluated on the fluoroscopy. We considered score 2 (acceptable) or 3 (excellent) as appropriate for localization. The staining extent of MLM was significantly smaller than methylene blue (0.6 vs 1.0 cm, P<0.001). MLM showed superior staining ability over methylene blue (2.8 vs 2.2, P=0.010). Excellent staining was achieved in 17 subjects (81%) with MLM and 8 (38%) with methylene blue (P=0.011). An acceptable or excellent radio-opacity of MLM was found in 13 subjects (62%). An appropriate localization rate of MLM was 100% with the use of the directly visible ability and radio-opacity of MLM. MLM provides a superior pulmonary localization ability over methylene blue.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Staining and Labeling / Thoracoscopy / Preoperative Care / Fluoroscopy / Tomography, X-Ray Computed / Solitary Pulmonary Nodule / Ethiodized Oil / Thoracic Surgery, Video-Assisted / Injections, Subcutaneous / Lung Limits: Animals Language: English Journal: Journal of Korean Medical Science Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Staining and Labeling / Thoracoscopy / Preoperative Care / Fluoroscopy / Tomography, X-Ray Computed / Solitary Pulmonary Nodule / Ethiodized Oil / Thoracic Surgery, Video-Assisted / Injections, Subcutaneous / Lung Limits: Animals Language: English Journal: Journal of Korean Medical Science Year: 2014 Type: Article