Factors affecting long-term survival after surgical resection of pancreatic ductal adenocarcinoma / 대한외과학회지
Journal of the Korean Surgical Society
;
: 394-401, 2011.
Article
in English
| WPRIM
| ID: wpr-200536
ABSTRACT
PURPOSE:
Some patients who undergo surgical resection of pancreatic cancer survive longer than other patients. The purpose of this study was to identify the factors that affect long-term survival after resection of histopathologically confirmed pancreatic ductal adenocarcinoma.METHODS:
A single-center, retrospective study was conducted among 164 patients who underwent surgical resection of pancreatic cancer, between May 1995 and December 2004. The patient follow-up process was conducted via telephone survey and review of electronic medical records for at least 5 years or until death.RESULTS:
We compared patients with long-term (> or =60 months, n = 19) and short-term survival (<60 months, n = 145). Resection margin status, differentiation of the tumor, tumor stage, pre-operative serum level of albumin, total bilirubin and carbohydrate antigen (CA) 19-9 level are related with survival difference (all factors, P < 0.05). Multivariate analysis revealed that a pre-operative serum total bilirubin level <7 mg/dL and a pre-operative serum CA19-9 level <37 U/mL is a statistically significant prognostic factor for long-term survival.CONCLUSION:
The preoperative serum total bilirubin and serum CA19-9 levels are associated with long-term survival after surgical resection of pancreatic cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pancreatic Ducts
/
Pancreatic Neoplasms
/
Telephone
/
Bilirubin
/
Adenocarcinoma
/
Multivariate Analysis
/
Retrospective Studies
/
Follow-Up Studies
/
Electronic Health Records
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Journal of the Korean Surgical Society
Year:
2011
Type:
Article
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