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Factors Associated with Delayed Neuropsychological Sequelae in Acute Carbon Monoxide Poisoning Patients Treated by Hyperbaric Oxygen
Journal of The Korean Society of Clinical Toxicology ; : 88-94, 2011.
Article in Korean | WPRIM | ID: wpr-20127
ABSTRACT

PURPOSE:

Delayed neuropsychological sequelae (DNS) commonly occurs after recovery from acute carbon monoxide poisoning. The aim of this article is to identify the factors associated with DNS development.

METHODS:

We retrospectively evaluated patients, admitted to the medical center emergency department from June 2005 to March 2011, who were suffering from acute carbon monoxide (CO) poisoning. We categorized the patients into two groups - those with DNS, and those without DNS. Multiple regression analysis was performed to identify the factors related to manifestation of DNS.

RESULTS:

Of the total one hundred fifty seven patients (157) recruited for the study, twenty two (22) developed DNS. Longer CO exposure times and lower GCS scores were positively associated with development of DNS symptoms.

CONCLUSION:

Our study identified two potential factors which are predictive of DNS development in CO intoxication, however, more studies are needed. Adequate follow-up after hospital discharge to monitor for and accurately identify manifestation of DNS, is also important.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Organothiophosphorus Compounds / Oxygen / Stress, Psychological / Carbon / Carbon Monoxide / Carbon Monoxide Poisoning / Retrospective Studies / Follow-Up Studies / Emergencies / Neuropsychology Type of study: Observational study / Prognostic study / Risk factors Limits: Humans Language: Korean Journal: Journal of The Korean Society of Clinical Toxicology Year: 2011 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Organothiophosphorus Compounds / Oxygen / Stress, Psychological / Carbon / Carbon Monoxide / Carbon Monoxide Poisoning / Retrospective Studies / Follow-Up Studies / Emergencies / Neuropsychology Type of study: Observational study / Prognostic study / Risk factors Limits: Humans Language: Korean Journal: Journal of The Korean Society of Clinical Toxicology Year: 2011 Type: Article