Extrapulmonary Small Cell Carcinoma of the Liver: Clinicopathological and Immunohistochemical Findings
Yonsei Medical Journal
;
: 1066-1071, 2007.
Article
in English
| WPRIM
| ID: wpr-201549
ABSTRACT
Patients with primary small cell carcinoma of the liver have rarely been described in medical literature. Knowledge of clinical, pathological and immunohistochemical properties remains limited. We described an 82-year-old female patient with primary small cell carcinoma of the liver. Histologically, the tumor showed typical morphology of a pulmonary small cell carcinoma. Immunohistochemically, the tumor revealed neuroendocrine differentiation; positive reaction for chromogranin, synaptophysin, CD56, and neuron specific enolase. The tumor was also positive for TTF-1 and c-kit but completely negative for hepatocyte, carcinoembryonic antigen, cytokeratin 7; 19; and 20. Herein, we discussed the clinical, pathological and immunohistochemical findings of extrapulmonary small cell carcinoma of the liver and reviewed the relevant literature.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phosphopyruvate Hydratase
/
Immunohistochemistry
/
Chromogranins
/
Synaptophysin
/
Carcinoma, Small Cell
/
CD56 Antigen
/
Liver
/
Liver Neoplasms
/
Lung Neoplasms
Type of study:
Diagnostic study
Limits:
Aged
/
Aged80
/
Female
/
Humans
Language:
English
Journal:
Yonsei Medical Journal
Year:
2007
Type:
Article
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