Factors influencing pregnancy rates in intrauterine insemination / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
;
: 1009-1016, 2005.
Article
in Korean
| WPRIM
| ID: wpr-202933
ABSTRACT
OBJECTIVE:
We have studied the factors that influence the pregnancy rate in ovarian hyperstimulation and intrauterine insemination (IUI) in infertility patients.METHODS:
Seventy two patients who visited the infertility clinic in Dongguk University Kyong-ju hospital from January 2002 to December 2003 underwent IUI after 99 cycles of ovarian hyperstimulation. We administered clomiphene with exogenous gonadotropin from cycle day 3 and then IUI was performed. The variables selected for retrospective analysis were patient's age (or=2), number of follicles (>or=2), size of dominant follicle (>or=18 mm), total sperm counts (>or=10 X 10(6)). Chi-square test, Fisher's exact test and a multiple logistic regression analysis were used to detect differences between groups in each variable.RESULTS:
The pregnancy rate per patient was 29.2% (21/72) and 21.2% (21/99) per cycle. Factors that influenced pregnancy rate were age, number of treatment cycles, number of preovulatory follicles (>or=16 mm), and total inseminated motile sperm counts, all of which showed significant differences (por=35), number of treatment cycles (2 cycle vs. 1 cycle), number of preovulatory follicles (>or=16 mm) (>or=3 vs. 1), and total inseminated motile sperm counts (>or=40 X 10(6) vs. <10 X 10(6)). The odds ratio of each of these variables were 12.6, 3.37, 11.64, and 10.59.CONCLUSION:
For successful pregnancy rates in IUI after ovarian hyperstimulation, the patient's age, number of treatment cycles, number of preovulatory follicles, and total inseminated motile sperm counts should be considered.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sperm Count
/
Logistic Models
/
Odds Ratio
/
Retrospective Studies
/
Clomiphene
/
Pregnancy Rate
/
Gonadotropins
/
Infertility
/
Insemination
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
/
Pregnancy
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
2005
Type:
Article
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