The Effect of intraperitoneal instillation of Mistletoe extract during the diagnostic laparoscopy for pain of endometriosis / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
;
: 1004-1008, 2005.
Article
in Korean
| WPRIM
| ID: wpr-202934
ABSTRACT
OBJECTIVE:
Immune alternation is related to the pathogenesis and progression of endometriosis. Helixor-A, mistletoe extract, has been known that it has immune modulation effect. Therefore the purpose of this study is to determine the effects of Helixor-A for pain of endometriosis by intraperitoneal instillation of mistletoe extract during the diagnostic laparoscopy.METHODS:
Among the paitients who visited to outpatient clinic due to chronic pelvic pain, 30 patients who had laparoscopically-confirmed endometriosis were included in this study. Helixor-A 5 mg was instilled into the posterior cul-de-sac during the diagnostic laparoscopy. Before diagnostic laparoscopy and one month after laparoscopy, the patients recorded pain scores.RESULTS:
In 11 of 30 patients (36.7%), pelvic pain of endometriosis improved after laparoscopy. In 2 of 30 patients, the side-effect of Helixor- A appeared and they were easily controlled by antihistamines.CONCLUSION:
The instillation of Helixor-A during diagnostic laparoscopy, that is essential for confirmation of endometriosis, may be helpful as a supportive treatment for treatment of pelvic pain due to endometriosis with classical treatment such as GnRH agonist therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Mistletoe
/
Gonadotropin-Releasing Hormone
/
Laparoscopy
/
Pelvic Pain
/
Endometriosis
/
Ambulatory Care Facilities
/
Histamine Antagonists
Type of study:
Diagnostic study
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
2005
Type:
Article
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