The Effect of Blood and Meconium Contamination on the TDx - FLM Assay for the Assessment of Fetal Lung Maturity / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
;
: 491-495, 1999.
Article
in Korean
| WPRIM
| ID: wpr-20303
ABSTRACT
OBJECTIVE:
We studied to determine the effect of blood or meconium contamination on the TDx-FLM assay for the assessment of fetal lung maturity. We also studied to evaluate the degree of diluted contaminants that affect the results.METHODS:
Nineteen samples of amnotic fluid-14 cases GA 37weeks-were collected and assayed for assessment of fetal lung maturity using tbe TDx-FLM assay. Among the above 19 samples, we used 12 samples-7 cases GA37 weeks-to contaminate with blood or meconium. Maternal blood was added to the amniotic fluid at increasing concentrations fro 110 to 11280. Diluted meconium (0.5g meconium/10ml amniotic fluid) was added at increasing concentration fiom 11 to 1128. Each samples were assessed by TDx assay.RESULTS:
TDx values in the cases of gestational age 37 weeks or more were matured level or borderline level(TDx value > 50mg/g), but below 37 weeks, TDx values wae immature level(TDx value < 50mg/g) except one case. In preterm cases, blood or meconium contamination did not affect the TDx values significantly, although the thick meamium contamination (diluted meconium amniotic fluid 11 - 14) increased the TDx values. In term cases, they did not affect the TDx values.CONCLUSION:
TDx test was suitable for the evaluation of fetal lung maturity regardless of blood or meconium contamination.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Gestational Age
/
Amniotic Fluid
/
Lung
/
Meconium
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
1999
Type:
Article
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