A Case of Scrotal Calcinosis Associated with Pilar Cyst / 대한피부과학회지

ABSTRACT

Idiopathic calcinosis of the scrotum appears in childhood as multiple, asymptomatic nodules of the scrotal skin that gradually increase in size and number and sometimes discharge a chalky material. Histopathologic examination shows calcific deposits of various sizes that are present in the dermis and often surrounded by foreign body granulomatous inflammation. The pathologic mechanism of this condition is not clear, but there is accumulating evidence for dystrophic calcification of cyst rather than an idiopathic genesis. Here we present a 34-year-old otherwise healthy man who had a 10-year history of multiple, asymptomatic, firm, subcutaneous nodules of the scrotal skin, which sometimes discharged a chalky material. The nodules were completely excised and 45 nodules were observed in the histopathologic examination. In addition to the typical findings of idiopathic calcinosis of the scrotum, seven intact cysts were observed among 45 nodules. Among the seven cysts there were five pilar cysts and two indeterminate cysts with diffusely calcified keratinous content and attenuated walls. A mixture of calcified keratinous material and inflammatory infiltrates was detected. These findings suggest that idiopathic calcinosis of the scrotum may be deriven from the dystrophic calcification of cysts.