Comparison of Autofluorescence Imaging Endoscopic Findings with Pathologic Findings after Endoscopic Submucosal Dissection of Gastric Neoplasms
Gut and Liver
;
: 186-192, 2008.
Article
in English
| WPRIM
| ID: wpr-203284
ABSTRACT
BACKGROUND/AIMS:
All epithelial cells emit autofluoresce, with tumor cells emitting weaker autofluorescence. We categorized patterns of autofluorescence imaging (AFI) and compared their clinical characteristics and pathology findings after endoscopic submucosal dissection.METHODS:
Twenty patients were enrolled, comprising 4 adenomas and 16 early gastric cancers. AFI findings were classified as follows G0 (well-defined pink lesion on a green background with a clear interface over > or =50% of its area), G1 (pink-green mottled lesion on a green background with a clear interface over <50% of its area), P1 (pink-green mottled lesion on a purple background with a clear interface over <50% of its area), and P2 (vague lesion on a purple background with a clear interface over < or =10% of its area).RESULTS:
Most of the patients (80%) were male, and their median age was 62.4 years (range 46-78 years). The lesion sizes by white-light mode, AFI mode, and pathology were 20.8+/-13.1, 22.8+/-15.4, and 20.0+/-17.7 mm (mean+/-SD), respectively. Sixteen cases of adenocarcinoma were classified as follows G0 (n=10), G1 (n=2), P1 (n=2), and P2 (n=2). The G0 group has no p53 positive lesions, unlike the non-G0 group (p=0.044). All cases with the P1 and P2 patterns were of the gastric and intestinal types, respectively.CONCLUSIONS:
AFI images of gastric tumors were categorized into four patterns that were useful for defining the resection margin in 87.5% of cases, with G0 being the most common pattern (62.5%).
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stomach Neoplasms
/
Adenocarcinoma
/
Adenoma
/
Enzyme Multiplied Immunoassay Technique
/
Epithelial Cells
/
Optical Imaging
Type of study:
Diagnostic study
Limits:
Humans
/
Male
Language:
English
Journal:
Gut and Liver
Year:
2008
Type:
Article
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