Capsular Genu Infarction Presenting with Confusional Syndrome: An Analysis of Clinical and Neuroradiologic Findings
Journal of the Korean Neurological Association
;
: 371-381, 1996.
Article
in Korean
| WPRIM
| ID: wpr-203675
ABSTRACT
We reviewed 5 patients with infarcts involving the genu of the internal capsule, who revealed behavioral changes and cognitive defects. They developed an acute confusion and/or dementic feature along with other behavioral changes characterized by apathy, hypersomnia, memory impairment, and cognitive impairment, mimicking frontal lobe dysfunction. Brain MRI and/or CT scan localized the lesion to the genu of the internal capsule. Brain perfusion SPECT performed in 3 patients showed hypoperfusion in ipsilateral cerebral hemisphere. Two mechanisms are suggested to explain the development of confusion or dementia after capsular genu infarct. (I) a disconnection or diaschisis of thalamo-cortical interconnection (ii) selective neuronal loss of cerebral cortex due to chronic MCA or ICA occlusion with insufficient collateral blood flow. We suggest that capsular-genu infarction as a cause of acute confusion or dementia must be included in differential diagnosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Perfusion
/
Brain
/
Magnetic Resonance Imaging
/
Tomography, X-Ray Computed
/
Tomography, Emission-Computed, Single-Photon
/
Cerebral Cortex
/
Internal Capsule
/
Dementia
/
Diagnosis, Differential
/
Cerebrum
Type of study:
Diagnostic study
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Neurological Association
Year:
1996
Type:
Article
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