Long-Term Survival after T-cell Lymphoblastic Lymphoma Treated with One Cycle of Hyper-CVAD Regimen / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
;
: 115-119, 2015.
Article
in English
| WPRIM
| ID: wpr-20369
ABSTRACT
T-lymphoblastic lymphoma (T-LBL) is a rare form of aggressive non-Hodgkin's lymphoma. The standard approach for management of T-LBL involves intensive multiagent chemotherapy regimens for induction and consolidation phases with central nervous system prophylaxis and a maintenance phase lasting 12-18 months. We report on a case of long-term survival after one cycle of hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone (hyper-CVAD) and high-dose methotrexate. A 30-year-old woman diagnosed with T-LBL with a large mediastinal mass underwent one cycle of hyper-CVAD. Four days after the start of treatment, the mediastinal mass was markedly reduced. Treatment continued with one cycle of consolidation chemotherapy, comprising high-dose methotrexate and high-dose cytarabine. The patient then refused all further chemotherapeutic treatment. Seven years have passed without relapse.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Vincristine
/
Lymphoma, Non-Hodgkin
/
Remission Induction
/
Dexamethasone
/
T-Lymphocytes
/
Doxorubicin
/
Central Nervous System
/
Methotrexate
/
Cyclophosphamide
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Cancer Research and Treatment
Year:
2015
Type:
Article
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