Renoprotective Effect of the Combined Use of Steroid and Angiotensin II Receptor Blocker in IgA Nephropathy / 대한신장학회잡지
Korean Journal of Nephrology
;
: 71-79, 2005.
Article
in Korean
| WPRIM
| ID: wpr-203775
ABSTRACT
BACKGROUND:
Several studies have examined the role of angiotensin II receptor blocker (ARB) or steroid treatment in decreasing proteinuria and preserving renal function in IgA nephropathy (IgAN).METHODS:
We designed a prospective, randomized trial to assess the effects of combination therapy of steroid (daily high-dose for 6 months) and ARB in IgAN patients with proteinuria >or=1.0 g/d and serum creatinine (SCr)or=1.4 mg/dL at the last visit had older age and higher proteinuria level at 6 mo than those with SCror=1g/d that the combination of ARB and prednisolone was more effective in preserving renal function as well as in decreasing proteinuria than the ARB alone therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Proteinuria
/
Immunoglobulin A
/
Angiotensin II
/
Angiotensins
/
Prednisolone
/
Receptors, Angiotensin
/
Prospective Studies
/
Creatinine
/
Glomerulonephritis, IGA
Type of study:
Controlled clinical trial
/
Observational study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Nephrology
Year:
2005
Type:
Article
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