Evaluation of Patients with Rheumatoid Arthritis by Tc-99m MIBI Imaging / 대한핵의학회잡지
Korean Journal of Nuclear Medicine
;
: 506-510, 2004.
Article
in Korean
| WPRIM
| ID: wpr-203798
ABSTRACT
PURPOSE:
We investigated whether Tc-99m MIBI imaging is useful to predict the response of drug treatment in patients with rheumatoid arthritis. MATERIALS ANDMETHODS:
24 patients (15 women and 9 men, age 49 +/- 12 year) rheumatoid arthritis and treated with disease modifying antirheumatic drugs (DMARDs) were included in this study. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were measured, and Tc-99m MIBI scan was obtained before drug treatment. Quantitative analysis of uptake in diseased joints was performed and expressed as joint-to background ratio (J/B) and percent retention (%R) of Tc-99m MIBI. Clinical symptoms were evaluated and graded from 0 (no) to 3 (severe) regarding to presence of tenderness and swelling.RESULTS:
J/B of the diseased joints were significantly correlated with ESR and CRP (p< 0.05). A highly significant correlation was found between the improvement of clinical symptoms and %R of Tc-99m MIBI (p< 0.05).CONCLUSION:
The results demonstrate that Tc-99m MIBI scan may be used to predict the therapeutic response in patients with rheumatoid arthritis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arthritis, Rheumatoid
/
Blood Sedimentation
/
C-Reactive Protein
/
Antirheumatic Agents
/
Joints
Limits:
Female
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Nuclear Medicine
Year:
2004
Type:
Article
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