Extraneural Metastasis of Glioblastoma Multiforme Presenting as an Unusual Neck Mass
Journal of Korean Neurosurgical Society
;
: 147-150, 2012.
Article
in English
| WPRIM
| ID: wpr-203812
ABSTRACT
Glioblastoma multiforme (GBM) is the most aggressive intracranial tumor and it commonly spreads by direct extension and infiltration into the adjacent brain tissue and along the white matter tract. The metastatic spread of GBM outside of the central nervous system (CNS) is rare. The possible mechanisms of extraneural metastasis of the GBM have been suggested. They include the lymphatic spread, the venous invasion and the direct invasion through dura and bone. We experienced a 46-year-old man who had extraneural metastasis of the GBM on his left neck. The patient was treated with surgery for 5 times, radiotherapy and chemotherapy. He had survived 6 years since first diagnosed. Although the exact mechanism of the extraneural metastasis is not well understood, this present case shows the possibility of extraneural metastasis of the GBM, especially in patients with long survival.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Brain
/
Central Nervous System
/
Glioblastoma
/
Neck
/
Neoplasm Metastasis
Limits:
Humans
Language:
English
Journal:
Journal of Korean Neurosurgical Society
Year:
2012
Type:
Article
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