A Correlation between the Severity of Lung Lesions on Radiographs and Clinical Findings in Patients with Severe Acute Respiratory Syndrome
Korean Journal of Radiology
;
: 466-474, 2007.
Article
in English
| WPRIM
| ID: wpr-203918
ABSTRACT
OBJECTIVE:
The purpose of this study was to quantify lesions on chest radiographs in patients with severe acute respiratory syndrome (SARS) and analyze the severity of the lesions with clinical parameters. MATERIALS ANDMETHODS:
Two experienced radiologists reviewed chest radiographs of 28 patients with SARS. Each lung was divided into upper, middle, and lower zones. A SARS-related lesion in each zone was scored using a four-point scale zero to three. The mean and maximal radiographic scores were analyzed statistically to determine if the scorings were related to the laboratory data and clinical course.RESULTS:
Forward stepwise multiple linear regression showed that the mean radiographic score correlated most significantly with the number of hospitalized days (p < 0.001). The second most significant factor was the absolute lymphocyte count (p < 0.001) and the third most significant factor was the number of days of intubation (p = 0.025). The maximal radiographic score correlated best with the percentage of lymphocytes in a leukocyte count (p < 0.001), while the second most significant factor was the number of hospitalized days (p < 0.001) and the third most significant factor was the absolute lymphocyte count (p = 0.013). The mean radiographic scores of the patients who died, with comorbidities and without a comorbidity were 11.1, 6.3 and 2.9, respectively (p = 0.032). The corresponding value for maximal radiographic scores were 17.7, 9.7 and 6.0, respectively (p = 0.033).CONCLUSION:
The severity of abnormalities quantified on chest radiographs in patients with SARS correlates with the clinical parameters.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Severity of Illness Index
/
Blood Gas Analysis
/
Biomarkers
/
Observer Variation
/
Survival Analysis
/
Predictive Value of Tests
/
Retrospective Studies
/
Lymphocyte Count
/
Severe Acute Respiratory Syndrome
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Radiology
Year:
2007
Type:
Article
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