Assessment of Cerebrovascular Reserve before and after STA-MCA Bypass Surgery by SPECT and SPM Analysis
Korean Journal of Radiology
;
: 458-465, 2007.
Article
in English
| WPRIM
| ID: wpr-203919
ABSTRACT
OBJECTIVE:
The purpose of this study was to objectively assess the efficacy of superficial temporal artery to middle cerebral artery (STA-MCA) bypass surgery using Technetium (Tc)-99m-ethyl cysteinate dimer (ECD) single photon emission computed tomography (SPECT) in patients who underwent STA-MCA bypass surgery. MATERIALS ANDMETHODS:
Brain perfusion SPECT images obtained at baseline and after the administration of acetazolamide were reconstructed using statistical parametric mapping in 23 patients, both before and after STA-MCA bypass surgery. The clinical outcomes of the surgery were also recorded and compared with the hemodynamic changes. A voxel with an uncorrected p-value of less than 0.001 was considered to be statistically significant.RESULTS:
SPECT images of the territory supplied by the bypass graft showed an increase in both cerebrovascular flow and reserve at baseline, and the increase was significantly higher following the administration of acetazolamide. All patients showed improvement of clinical symptoms and increased blood flow to the left temporal, parietal, and frontal cortices as well as the thalamus.CONCLUSION:
Brain SPECT effectively and objectively demonstrated the improved outcomes of STA-MCA bypass surgery, and thus may be used in postoperative analyses.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Temporal Arteries
/
Image Processing, Computer-Assisted
/
Brain
/
Brain Mapping
/
Organotechnetium Compounds
/
Tomography, Emission-Computed, Single-Photon
/
Intracranial Arteriosclerosis
/
Cerebral Revascularization
/
Cerebrovascular Circulation
/
Predictive Value of Tests
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Radiology
Year:
2007
Type:
Article
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