Comparative Study of 20% Aluminum Chloride Solution and Botulinum Toxin A Injection in the Treatment of Patients with Primary Palmar Hyperhidrosis / 대한피부과학회지
Korean Journal of Dermatology
;
: 334-340, 2008.
Article
in Korean
| WPRIM
| ID: wpr-204120
ABSTRACT
BACKGROUND:
Primary hyperhidrosis carries a substantial psychological and social burden. Early detection and management can significantly improve a patient's quality of life. A large number of therapeutic options are used, such as the application of topical agents, iontophoresis, sympathectomy, and botulinum toxin injection.OBJECTIVE:
We aim to comprehensively evaluate the effects of botulinum toxin type A and 20% aluminum chloride on primary palmar hyperhidrosis.METHODS:
A total of 55 patients with clinical diagnosis of primary hyperhidrosis were treated by botulinum toxin type A and 20% aluminum chloride solution. To prospectively assess the effects on primary palmar hyperhidrosis, we checked corneometer at baseline, 2 and 4 months later. By regular meetings with patients, including telephone interviews, we analyzed patients' subjective satisfaction scores and complaints during the follow=up periods.RESULTS:
During the 2-month period, as compared with that of the control group, the level of corneometer of both groups declined. In the 4-month period, the group treated with 20% aluminum chloride sustained a lower level of corneometer. In the questionnaire, in the 2-month period, the group treated with botulinum toxin resulted in a lower level of overall treatment scores than that of the group treated with 20% aluminum chloride. However, in the 4-month period, the group treated with aluminum chloride showed lower scores.CONCLUSION:
Both botulinum toxin type A and aluminum chloride solution were safe and well tolerated, producing high levels of patient satisfaction. However, considering the long-term efficacy of treatment, aluminum chloride may be a more suitable mode of treatment for primary palmar hyperhidrosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quality of Life
/
Sympathectomy
/
Botulinum Toxins
/
Chlorides
/
Iontophoresis
/
Interviews as Topic
/
Prospective Studies
/
Surveys and Questionnaires
/
Patient Satisfaction
/
Aluminum Compounds
Type of study:
Observational study
/
Qualitative research
/
Screening study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2008
Type:
Article
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