Hemodynamic and Catecholamine Responses to Laryngoscopy and Endotracheal Intubation in Paraplegic Patients: Time Course and Relation to the Affected Level / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 160-166, 2008.
Article
in Korean
| WPRIM
| ID: wpr-204180
ABSTRACT
BACKGROUND:
We determined whether the cardiovascular responses to endotracheal intubation change as a function of the time elapsed after injury and the level of injury in patients with spinal cord injury.METHODS:
One-hundred-eighty six patients with complete cord injury were grouped into 3 according to the level of injuryhigh- (T1-T4, n = 34), mid- (T5-T10, n = 47) and low paraplegics ( 10 yrs.Twenty-five patients with no cord injury served as controls.Systolic arterial blood pressure (SAP), heart rate (HR), and plasma catecholamine concentrations were measured.RESULTS:
The intubation caused an increase of SAP and norepinephrine concentrations in every group.However, the magnitude of their peak increases was less in high paraplegics compared with all other groups (P < 0.05).HR was similarly increased in all groups (P < 0.01).Pressure but not either HR or norepinephrine response was enhanced in mid- and low-paraplegics whose injury elapsed more than 10 yrs compared with controls (P < 0.05).The incidence of arrhythmias did not differ among the groups.CONCLUSIONS:
The pressure and plasma catecholamine changes associated with endotracheal intubation may be attenuated in high-paraplegics, and the pressure changes may be enhanced over time in mid- and low-paraplegics.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plasma
/
Arrhythmias, Cardiac
/
Spinal Cord Injuries
/
Tachycardia
/
Norepinephrine
/
Incidence
/
Arterial Pressure
/
Heart Rate
/
Hemodynamics
/
Hypertension
Type of study:
Incidence study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
2008
Type:
Article
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