A Case of Disseminated Infection Due to Scedosporium apiospermum in a Liver-transplantation Recipient / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 421-424, 2005.
Article
in Korean
| WPRIM
| ID: wpr-204217
ABSTRACT
Scedosporium apiospermum, an anamorph of Pseudallescheria boydii, is a ubiquitous saprophytic mold. Now a day, S. apiospermum is an emerging pathogen related to a significant morbidity and high mortality in transplant recipients. For the first time in Korea, we report a case of disseminated infection caused by S. apiospermum after liver transplantation. A 47-year-old woman underwent living donor liver transplantataion for billiary cirrhosis. She was treated with cyclosporine A, methylprednisolone, and prophylactic antibiotics including amphotericin B. She was found to have developed pneumonia and brain abscess at postoperative day 9 and 17 by chest X-ray and brain CT, respectively. Cultures of endotracheal aspirates and aspirates of brain abscess yielded S. apiospermum. Despite of antifungal therapy with amphotericin B, voriconazole, and caspofungin and removal of mycotic aneurysm of the brain, the patient died on postoperative day 33.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia
/
Thorax
/
Transplantation
/
Fibrosis
/
Aneurysm, Infected
/
Brain
/
Brain Abscess
/
Pseudallescheria
/
Methylprednisolone
/
Amphotericin B
Type of study:
Prognostic study
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
The Korean Journal of Laboratory Medicine
Year:
2005
Type:
Article
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