Febrile Urinary Tract Infections Caused by Community-Acquired Extended-Spectrum beta-Lactamase-Producing and-Nonproducing Bacteria: A Comparative Study
Pediatric Infection & Vaccine
;
: 29-35, 2015.
Article
in Korean
| WPRIM
| ID: wpr-204527
ABSTRACT
PURPOSE:
The purpose of this study was to investigate the clinical characteristics and outcome of febrile urinary tract infections (UTIs) caused by community-acquired extended-spectrum beta-lactamase (CA-ESBL)-producing and -nonproducing bacteria.METHODS:
We analyzed febrile UTIs in children hospitalized at Gachon University Gil Medical Center from January 2011 to December 2013 through retrospective data collection from their medical records.RESULTS:
Among pathogens causing 374 episodes of UTIs, the proportion of ESBL-producing bacteria was 13.1% (49/374). The proportion of ESBL-producing Escherichia coli and Klebsiella spp. was 13.6% (48/354) and 5.0% (1/20), respectively. There was no significant difference between the CA-ESBL and CA non-ESBL groups in duration of fever (4.2+/-2.7 vs.3.7+/-2.1 days, P=0.10) and bacterial eradication rate with empirical antibiotics (100% vs. 100%). The risk of cortical defects on renal scan significantly depended on existence of vesicoureteral reflux rather than ESBL production of pathogen.CONCLUSIONS:
There was no significant difference between the CA-ESBL and CA non-ESBL groups in renal cortical defects and clinical outcome. Careful choice of antibiotics is important for treatment of community-acquired UTI in children.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Bacteria
/
Urinary Tract Infections
/
Vesico-Ureteral Reflux
/
Beta-Lactamases
/
Medical Records
/
Data Collection
/
Retrospective Studies
/
Escherichia coli
/
Fever
/
Klebsiella
Type of study:
Observational study
Limits:
Child
/
Humans
Language:
Korean
Journal:
Pediatric Infection & Vaccine
Year:
2015
Type:
Article
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