A Case of Gianotti-Crosti Syndrome Associated with Epstein-Barr Virus Infection / 대한피부과학회지

ABSTRACT

Gianotti-Crosti syndrome(GCS) is a distinct exanthematic, acrolocated eruption of childhood caused by a variety of infectious agents. Historically hepatitis B antigen positive(HBsAG+) papular acrodermatitis of childhood and HBsAg negative(HBsAg-) papulovesicular acrolocated syndrome have been distinguished. Here we present a 22-month-old female patient who developed eruptions typical for GCS and showed serologic evidence of an acute Epstein-Barr virus(EBV) infection. Serologic investigations revealed no evidence of recent infection with most common viruses except EBV infection. This case suggests that EBV infection should be sought in cases of GCS which cannot be related to HBV infection.