The efficacy of thymopentin in the treatment of atopic dermatitis / 천식및알레르기
Journal of Asthma, Allergy and Clinical Immunology
;
: 640-646, 1998.
Article
in Korean
| WPRIM
| ID: wpr-204959
ABSTRACT
BACKGROUND:
Thymopentin(TP-5) is an immunomodulatory agent which may be a promising new drug in the treatment of patients with severe atopic dermatitis.OBJECTIVE:
The aim of this study was to evaluate the efficacy of thymopentin for treatment of severe atopic dermatitis. MATERIAL ANDMETHOD:
Fifteen patients with severe atopic dermatitis received subcutaneous injections of 50mg thymopentin three times per week for 6 weeks. Clinical extent and severity parameters were assessed at baseline, at regular intervals during therapy and 4 weeks posttherapy. Use of antihistamine and topical steroid were permitted.RESULT:
Significant reduction in severity scores and body surface area involvement was observed and no significant side effects were noted(p<0.05).CONCLUSION:
Thymopentin may be considered to be an effective adjunctive therapeutic agent in the treatment of severe atopic dermatitis. Further studies will be needed to determine the action mechanism of thymopentin.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Body Surface Area
/
Thymopentin
/
Dermatitis, Atopic
/
Injections, Subcutaneous
Limits:
Humans
Language:
Korean
Journal:
Journal of Asthma, Allergy and Clinical Immunology
Year:
1998
Type:
Article
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