Inherited Vitamin K Deficiency: Case Report and Review of Literature
Yonsei Medical Journal
;
: 923-927, 2003.
Article
in English
| WPRIM
| ID: wpr-205353
ABSTRACT
Vitamin K is the cofactor for the hepatic carboxylation of glutamic acid residues in a number of proteins including the procoagulants factors ll, Vll, lX, and X. The role of vitamin K in normal bone function is not fully understood. Inherited deficiency of vitamin K dependent coagulation factors is a rare bleeding disorder reported only in a few patients. Here we present an 18-month old child who presented with osteopeni due to inherited vitamin K deficiency. While the patient had high bone specific alkaline phosphatase and parathyroid hormone levels and low osteocalcin and bone mineral density values, with the regular supplementation of vitamin K all the mentioned parameters returned to normal values.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prothrombin Time
/
Vitamin K Deficiency
/
Bone Diseases, Metabolic
/
Bone Density
/
Osteocalcin
Limits:
Humans
/
Infant
/
Male
Language:
English
Journal:
Yonsei Medical Journal
Year:
2003
Type:
Article
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