Phototherapeutic Keratectomy for Granular Corneal Dystrophy
Journal of the Korean Ophthalmological Society
;
: 2465-2472, 2003.
Article
in Korean
| WPRIM
| ID: wpr-205413
ABSTRACT
PURPOSE:
In this study, we evaluated the results of PTK(phototherapeutic keratectomy) for granular corneal dystrophy.METHODS:
5 eyes (4 patients) with granular corneal dystrophy were treated by PTK using Summit ExiMed UV200 and VSIX Star excimer laser systems. The epithelium was removed mechanically with a surgical blade. We used methylcellulose 1.0% as a surface modulator before laser ablation. Focal ablations of the central cornea with an ablation zone of 6.0 mm were performed. Mean ablation depth was 105 +/- 15.81 micrometer (range; 80~120 micrometer) Additional hyperopic PRK was performed on 4 eyes out of 5 eyes at the corneal mid-periphery up to maximum +5.00 D to prevent post-PTK hyperopic shift. Mean follow up period was 54.4 +/- 23.43months (range; 24~84months).RESULTS:
Removal of corneal opacities allowed for improvement in both uncorrected visual acuity and best corrected visual acuity in all patients. There was an improvement in best-corrected visual acuity of a mean of 2.6 lines on the Snellen chart. Mean corneal thickness in the area of pathology decreased from 490.5 micrometer before surgery to 391.5 micrometer after surgery. There was a hyperopic shift in all the eyes in spite of additional hyperopic PRK by a mean of +2.44 +/- 0.99 D. There was mild recurrent dystrophic change in an eye but not significant enough to affect visual acuity during the follow up period. No major complications developed in any patients.CONCLUSIONS:
Our results suggest that PTK is a safe and effective alternative to penetrating and lamellar keratoplasty in patients with granular corneal dystrophy. Mild post-PTK hyperopic shift occurred in all patients in spite of combined hyperopic PRK up to maximum +5.00 D correction at the corneal mid- peripheral zone according to the refractive powers.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Visual Acuity
/
Follow-Up Studies
/
Corneal Transplantation
/
Cornea
/
Corneal Opacity
/
Epithelium
/
Laser Therapy
/
Lasers, Excimer
/
Methylcellulose
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2003
Type:
Article
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