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Changes in Pathogens and Antibiotic Sensitivities in very Low Birth Weight Infants with Neonatal Sepsis
Journal of the Korean Society of Neonatology ; : 54-60, 2008.
Article in Korean | WPRIM | ID: wpr-205504
ABSTRACT

PURPOSE:

To set up an appropriate treatment plan for neonatal sepsis by investigating changes in pathogens and antibiotic sensitivities.

METHODS:

The medical records of very low birth weight infants (VLBWI) admitted to the neonatal intensive care unit (NICU) of the Eulji University Hospital between January 2000 and June 2006 were retrospectively reviewed. The culture reports were analyzed for causative microorganisms and antibiotic sensitivities.

RESULTS:

Among 164 neonates, 19 neonates (11.6%) had 26 episodes of culture-proven sepsis. Very late onset sepsis was the most common type. The dominant pathogens of sepsis included Klebsiella pneumoniae, Streptococcus spp., coagulase negative Staphylococcus and Enterobacter spp., and were mostly multi-drug resistant.

CONCLUSION:

For the appropriate treatment of neonatal sepsis, proper use of antibiotics through the periodic review and understanding of changes of the microorganisms and antimicrobial sensitivities is necessary to prevent multi-drug resistant microorganisms and to avoid excessive use of broad-spectrum empiric antibiotics.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Staphylococcus / Streptococcus / Intensive Care, Neonatal / Medical Records / Retrospective Studies / Coagulase / Sepsis / Infant, Very Low Birth Weight / Enterobacter / Klebsiella pneumoniae Type of study: Diagnostic study / Observational study Limits: Humans / Infant / Infant, Newborn Language: Korean Journal: Journal of the Korean Society of Neonatology Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Staphylococcus / Streptococcus / Intensive Care, Neonatal / Medical Records / Retrospective Studies / Coagulase / Sepsis / Infant, Very Low Birth Weight / Enterobacter / Klebsiella pneumoniae Type of study: Diagnostic study / Observational study Limits: Humans / Infant / Infant, Newborn Language: Korean Journal: Journal of the Korean Society of Neonatology Year: 2008 Type: Article