Correlation of Cord Serum Adiponectin and IGF-I with Fetal Growth in Healthy Term Neonates
Journal of the Korean Society of Neonatology
;
: 38-43, 2008.
Article
in Korean
| WPRIM
| ID: wpr-205506
ABSTRACT
PURPOSE:
The purpose of this study was to evaluate the relationship between cord serum adiponectin (APN) and IGF-I concentrations and fetal growth.METHODS:
Umbilical cord serum APN and IGF-I concentrations were measured in healthy term singleton deliveries (n=72). The association of cord serum APN and IGF-I concentrations was evaluated in relation to birth weight, height, head circumference, gender, ponderal index, placental weight, feto-placental (F/P) weight ratio, maternal weight gain, and maternal body mass index (BMI).RESULTS:
The mean cord serum APN was 29.2+/-10.46 microgram/mL. The cord serum APN and birth weight demonstrated a bell-shape relationship. The cord serum APN concentration was higher in females than males (P=0.001). The cord serum APN was negatively correlated with maternal BMI (r=-0.301, P=0.027), but the mean cord serum APN concentration was not correlated with birth height, birth head circumference, ponderal index, placental weight, F/P ratio, or maternal weight gain. The mean cord serum concentrations of IGF-I was 51.26+/-21.54 ng/mL. The cord serum IGF-I concentration was positively correlated with birth weight (r=0.312, P=0.009), but not birth height, ponderal index, placental weight, F/P weight ratio, or maternal BMI.CONCLUSION:
APN demonstrated a bell-shaped relationship with birth weight in healthy term infants. IGF-I was highly correlated with fetal growth, especially birth weight.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Umbilical Cord
/
Birth Weight
/
Insulin-Like Growth Factor I
/
Weight Gain
/
Body Mass Index
/
Parturition
/
Fetal Development
/
Adiponectin
/
Head
Limits:
Female
/
Humans
/
Infant
/
Male
/
Infant, Newborn
Language:
Korean
Journal:
Journal of the Korean Society of Neonatology
Year:
2008
Type:
Article
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