Endoscopic Closure for Full-Thickness Gastrointestinal Defects: Available Applications and Emerging Innovations
Clinical Endoscopy
;
: 438-443, 2016.
Article
in English
| WPRIM
| ID: wpr-205870
ABSTRACT
Full-thickness gastrointestinal defects such as perforation, anastomotic leak, and fistula are severe conditions caused by various types of pathologies. They are more likely to require intensive care and a long hospital stay and have high rates of morbidity and mortality. After intentional full-thickness opening of hollow organs for natural orifice transluminal endoscopic surgery, safe and secure closure is urgently required. The currently available advanced endoscopic closing techniques have a major role in the treatment of full-thickness gastrointestinal defects. Appropriate usage of these techniques requires taking into account their advantages and limitations during practical application. We reviewed the available endoscopic modalities, including endoscopic clips, stents, vacuum-assisted closure, gap filling, and suturing devices, discussed their advantages and limitations when treating full-thickness gastrointestinal defects, and explored emerging innovations, including a novel endoluminal surgical platform for versatile suturing and a cell-laden scaffold for effective gap filling. Although these emerging technologies still require further pre-clinical and clinical trials to assess their feasibility and efficacy, the available modalities may be replaced and refined by these new techniques in the near future.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Stents
/
Mortality
/
Critical Care
/
Negative-Pressure Wound Therapy
/
Anastomotic Leak
/
Natural Orifice Endoscopic Surgery
/
Fistula
/
Length of Stay
Type of study:
Prognostic study
Language:
English
Journal:
Clinical Endoscopy
Year:
2016
Type:
Article
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