Protective Effects of Viscoelastic Substances on air Bubble Damage During Phacoemulsification
Journal of the Korean Ophthalmological Society
;
: 2273-2279, 2002.
Article
in Korean
| WPRIM
| ID: wpr-20612
ABSTRACT
PURPOSE:
To determine whether viscoelastic materials are effective to protect the corneal endothelium from air bubble damage.METHODS:
Human eye bank (n=12) and rabbit (n=22) eyes underwent a standardized phacoemulsification procedure with or without viscoelastic material [1% sodium hyaluronate (Healon(R)), 1.4% sodium hyaluronate (Healon GV(R)), 3% sodium hyaluronate with 4% chondroitin sulfate (Viscoat(R))]. The integrity of the endothelium was examined after the procedure with F-actin staining and scanning electron microscopy (SEM).RESULTS:
In the phacoemulsification experiment without viscoelastic material, with Healon, and with Healon GV, the endothelium of both human and rabbit corneas had many areas of cell loss in a pattern consistent with air bubble damage. But with Viscoat, endothelial cells remained intact.CONCLUSIONS:
We found that Viscoat was effective to protect the endothelium from air bubble damage. Viscoat seems to protect the endothelium by acting as a physical barrier.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Endothelium, Corneal
/
Microscopy, Electron, Scanning
/
Chondroitin Sulfates
/
Actins
/
Phacoemulsification
/
Cornea
/
Endothelial Cells
/
Endothelium
/
Eye Banks
/
Viscoelastic Substances
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2002
Type:
Article
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