Immunoglobulin E-mediated hypersensitivity reaction after intraperitoneal administration of vancomycin
Kidney Research and Clinical Practice
;
: 57-59, 2015.
Article
in English
| WPRIM
| ID: wpr-206923
ABSTRACT
Intraperitoneal (IP) vancomycin is widely used to treat Gram-positive peritonitis associated with peritoneal dialysis. There have been two cases of red man syndrome (RMS), a vancomycin-specific nonimmunologic reaction, associated with IP vancomycin. However, immune-mediated hypersensitivity reaction to IP vancomycin has not yet been reported. A 49 year old woman on continuous ambulatory peritoneal dialysis developed her first peritonitis episode. The patient was treated with IP vancomycin once/wk for 4 weeks. She experienced mild itching and flushing throughout her body for 1 day after the second treatment. Whenever vancomycin was administered, generalized urticaria and a prickling sensation developed, and the intensity increased gradually; however, these symptoms improved after vancomycin was discontinued. An allergic skin test was performed 6 weeks after the previous urticarial episode, and an intradermal skin test revealed a positive response to vancomycin. To our knowledge, this is the first case report of immunoglobulin E-mediated hypersensitivity reaction to IP vancomycin administration.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peritonitis
/
Pruritus
/
Sensation
/
Urticaria
/
Immunoglobulins
/
Skin Tests
/
Vancomycin
/
Peritoneal Dialysis
/
Peritoneal Dialysis, Continuous Ambulatory
/
Flushing
Limits:
Female
/
Humans
Language:
English
Journal:
Kidney Research and Clinical Practice
Year:
2015
Type:
Article
Similar
MEDLINE
...
LILACS
LIS