Silicone oil keratopathy
Korean Journal of Ophthalmology
;
: 65-69, 1993.
Article
in English
| WPRIM
| ID: wpr-207395
ABSTRACT
Light microscopy and electron microscopic examination were carried out on the corneal buttons of two patients who required penetrating keratoplasty for treatment of corneal complication following the intraocular injection of silicone oil to repair recurrent retinal detachments in aphakic eyes. Light microscopic examination demonstrated increased cellularity and irregularity of collagen fibers of stromal layer, defect of endothelial cell layer and endothelial degeneration. Electron microscopy examination demonstrated marked decrease in endothelial cell population density, accompanied by flattening and thinning of the remaining cells and attenuation of cell borders. There were silicone droplets in the endothelial cell layer and collagenous layer posterior to endothelial layer. These findings are well correlated to clinical manifestation and are thought to be rather due to barrier effect of silicone oil than direct toxicity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Silicone Oils
/
Retinal Detachment
/
Endothelium, Corneal
/
Keratoplasty, Penetrating
/
Corneal Diseases
/
Descemet Membrane
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Ophthalmology
Year:
1993
Type:
Article
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